PT  - JOURNAL ARTICLE
AU  - Muhannad A. Asiri
AU  - Mohammed S. Alqahtani
AU  - Saeed A. Alqahtani
AU  - Mohammed M. Alwadai
AU  - Naif F. Alharbi
AU  - Mohammed O. Aqeeli
AU  - Saeed S. Alzahrani
TI  - Incidence and risk factors of contrast-induced nephropathy in acute stroke patients undergoing computed tomography angiography: A single-center study
AID  - 10.17712/nsj.2023.4.20230030
DP  - 2023 Oct 01
TA  - Neurosciences Journal
PG  - 258--263
VI  - 28
IP  - 4
4099  - http://nsj.org.sa/content/28/4/258.short
4100  - http://nsj.org.sa/content/28/4/258.full
SO  - Neurosciences (Riyadh)2023 Oct 01; 28
AB  - Objectives: To investigate the prevalence and risk factors linked to contrast-induced nephropathy in this specific patient population, aiming to ensure the highest quality of clinical care.Methods: In a retrospective analysis, all patients who presented with an acute stroke to King Fahad Hospital, Jeddah, Emergency Department from March until November 2022 and underwent Computed Tomography Angiography (CTA) brain, Inclusion criteria were as follows: a baseline creatinine results and CTA examination performed within 24 hours of symptom onset and an available early (<5 days after CTA) follow-up creatinine result.Results: Among 246 stroke patients in the emergency, 182 underwent brain CTA and 8.24% had Contrast-Induced Nephropathy (CIN). intracerebral hemorrhage (ICH) increased CIN risk 7-fold (OR=6.7; 95% CI: 1.23-33.3). Abnormal baseline raised CIN risk 8-fold (OR=7.8; 95% CI: 1.74-35.1). hypertension doubled the risk for CIN (OR=2.1; 95% CI: 1.26-6.98)Conclusion: The incidence of CIN was 8.2%, particularly elevated in patients with ICH, hypertension, tissue plasminogen administration, and abnormal baseline, necessitating vigilance in managing acute stroke cases.