Objectives: To report the efficacy of intravenous (IV) synthetic ACTH (Tetracosactide) in the
treatment of infantile spasms. Methods: This is a retrospective chart review of patients with a …

Background High dosages of natural adrenocorticotropic hormone are used in many centers
in the United States for the treatment of infantile spasms. However, lower dosages of …

Of 363 infants with infantile spasms (IS) admitted into our hospital during an 18-year period,
286 were closely followed for at least 6 years and form the basis of this report. These …

The relationship between the dose of ACTH and the initial effect was investigated in 41
children with infantile spasms. More than 0.015 mg (0.6 IU)/kg/day of ACTH was needed for …

There is insufficient evidence to recommend a specific protocol for treatment of infantile
spasms (IS) and a lack of standardization among, and even within, institutions. Twice-daily …

We investigated the effect of long-term, low-dose ACTH in 13 patients (10 boys and 3 girls)
with infantile spasms who were treated with low-dose ACTH (mean: 0.0081 mg/kg/day). Two …

Ten infants with infantile spasms (IS) and hypsarrhytmic EEC, received 0.5 mg im of
synthetic ACTH, three times a week for 2 weeks. Six of them showed complete remission of …

Objective: To evaluate and assess the efficacy of ACTH and Vigabatrin in Symptomatic
variety of Infantile Spasm in Pakistani patients to document local experience. Methodology …

Infantile spasms are a seizure disorder in young infants with diverse etiologies, suggesting
that they arise from any disturbance of central nervous system function during susceptible …

A controlled study of 5 patients with infantile spasms was performed to détérmine the
effectiveness of corticotropin (ACTH) treatment. Patients were monitored serially, using a …