RT Journal Article
SR Electronic
T1 Comparison of the efficacy of prednisolone versus prednisolone and acyclovir in the treatment of Bell’s palsy
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 256
OP 259
VO 11
IS 4
A1 Ahangar, Alijan A.
A1 Hosseini, Seydreza
A1 Saghebi, Roshanak
YR 2006
UL http://nsj.org.sa/content/11/4/256.abstract
AB OBJECTIVE: To compare the efficacy of 2 regimens of prednisolone versus prednisolone and acyclovir in the treatment of Bell’s palsy.METHODS: A retrospective study was performed on 496 Bell’s palsy patients attending Yahyanejad Hospital, Babol, Iran from 1995 to 2004, divided in 2 groups. The first group was treated with regimen one (oral prednisolone), and the second group was treated with regimen 2 (oral prednisolone plus oral acyclovir) for 2 weeks. All cases were followed for 6 months.RESULTS: Two hundred and forty-eight cases (108 males, 140 females) were treated with regimen one, and 248 cases (113 males, 135 females), were treated with regimen 2. Both groups had a mean age of 20-39 years. At the end of therapy, the recovery rate with regimen 2 was 95.6% (237 patients), whereas regimen one showed a recovery rate of 91.2% (226 patients) (p=0.047).CONCLUSION: This study showed acyclovir plus prednisolone to be more effective than prednisolone alone in the treatment of Bell’s palsy.