PT  - JOURNAL ARTICLE
AU  - Grira, Mounir T.
AU  - Ben Jemaa, Haifa M.
AU  - Lammouchi, Turkia M.
AU  - Benammou, Sofien A.
TI  - Meningitis revealing pancreatic carcinoma
DP  - 2007 Jul 01
TA  - Neurosciences Journal
PG  - 256--258
VI  - 12
IP  - 3
4099  - http://nsj.org.sa/content/12/3/256.short
4100  - http://nsj.org.sa/content/12/3/256.full
SO  - Neurosciences (Riyadh)2007 Jul 01; 12
AB  - Meningeal carcinomatosis is an uncommon metastatic complication of systemic solid tumors. The diagnosis is based on the presence of malignant cells in the cerebrospinal fluid. The sensibility of cerebrospinal fluid testing in detecting the neoplastic cells improves when repeating lumbar punctures. Magnetic resonance imaging could help in establishing the diagnosis. The prognosis of carcinomatous meningitis is poor, especially when the primitive neoplasm is initially unknown. We report the case of a patient presenting with sudden bilateral visual decrease, headaches, and vomiting. Signs of meningeal irritation were found. Cerebrospinal fluid analysis showed malignant cells consistent with an adenocarcinoma. Abdominal echography and MRI concluded in a nodule of the cephalic portion of the pancreas. Carcinomatous meningitis rarely complicates pancreatic cancers.