PT  - JOURNAL ARTICLE
AU  - Roshan Koul
AU  - Amna Al-Futaisi
AU  - Ranjan Williams
AU  - Hashim Javad
AU  - Alexander Chacko
TI  - Transient opsoclonus-myoclonus syndrome secondary to neuroblastoma
DP  - 2007 Jul 01
TA  - Neurosciences Journal
PG  - 253--255
VI  - 12
IP  - 3
4099  - http://nsj.org.sa/content/12/3/253.short
4100  - http://nsj.org.sa/content/12/3/253.full
SO  - Neurosciences (Riyadh)2007 Jul 01; 12
AB  - We report a 2.5-year-old girl who presented with acute history of fluctuating level of consciousness in the form of drowsiness, extreme irritability, and involuntary abnormal movements in the form of shaking of the whole body. She was treated with acyclovir empirically, contemplating herpes simplex virus encephalitis. Overtime she improved substantially. The opsoclonus, myoclonus, and ataxia disappeared without treatment. However, 6 weeks later she presented again with classic opsoclonus-myoclonus syndrome. The investigations revealed neuroblastoma. This case illustrates that transient opsoclonus-myoclonus may occur with neuroblastoma and should not be assumed to be due to viral cause. Thus, a thorough search for occult neuroblastoma should be initiated even if opsoclonus-myoclonus resolves spontaneously.