PT  - JOURNAL ARTICLE
AU  - Alfayez, Shaden S.
AU  - Hamad, Muddathir H.
AU  - Kentab, Amal Y.
AU  - Alanezi, Ahmad A.
AU  - Kurdi, Daniah M.
AU  - Almuhideb, Hanady A.
AU  - Bashiri, Fahad A.
TI  - Risk factors, clinical characteristics, and outcomes of perinatal stroke in a Tertiary University Hospital
AID  - 10.17712/nsj.2025.2.20240089
DP  - 2025 Apr 01
TA  - Neurosciences Journal
PG  - 138--143
VI  - 30
IP  - 2
4099  - http://nsj.org.sa/content/30/2/138.short
4100  - http://nsj.org.sa/content/30/2/138.full
SO  - Neurosciences (Riyadh)2025 Apr 01; 30
AB  - Objectives: To investigate the risk factors, clinical characteristics, and neurodevelopmental outcomes associated with perinatal stroke, as well as to assess the risk of epilepsy, seizure control, and cognitive function in children with perinatal stroke.Methods: Data from 32 patients diagnosed with perinatal stroke between October 2007 and October 2020 were retrospectively reviewed.Results: Of 32 patients, 27 were born after normal pregnancies, and 20 (62.5%) had consanguineous parents. Family histories of stroke, haematological disease, and epilepsy were noted in 3.13%, 3.13%, and 21.88%, respectively. Initial symptoms included hemiparesis (56.25%), seizures (37.5%), respiratory distress (3.13%), and tiptoe walking (3.13%). Epilepsy was diagnosed in 22 patients, with 72.72% achieving seizure control. Among 12 patients who underwent IQ testing, 15.63% had borderline impairment, 9.37% average IQ, 3.13% below-average IQ, and 6.26% moderate-to-severe impairment.Conclusion: Hemiparesis was the most frequent presenting symptom, followed by seizures. Many patients developed epilepsy, with most achieving satisfactory seizure control. IQ testing revealed varying degrees of cognitive impairment, highlighting the complex neurodevelopmental effects of perinatal stroke.