PT - JOURNAL ARTICLE AU - Yasseen, Akeel A. AU - Al-Musawi, Thekra A. TI - Metaphase acrocentric associations in metally retarded patients DP - 2001 Oct 01 TA - Neurosciences Journal PG - 233--237 VI - 6 IP - 4 4099 - http://nsj.org.sa/content/6/4/233.short 4100 - http://nsj.org.sa/content/6/4/233.full SO - Neurosciences (Riyadh)2001 Oct 01; 6 AB - OBJECTIVE: The metaphase of 21 severely mentally retarded patients were studies to assess the role of satellite association in the etiology of mental retardation.METHODS: Peripheral blood culture, chromosome harvesting and study scoring were conducted according to standard methods.RESULTS: Considered as a whole the results indicate that there is a significant increase in the frequency of satellite association among the mentally retarded.CONCLUSION: The present study concluded that satellite association may play a role in the etiology of mental retardation and may explain to some extent the presence of normal karyotype in some mental retardation patients.