RT Journal Article
SR Electronic
T1 Metaphase acrocentric associations in metally retarded patients
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 233
OP 237
VO 6
IS 4
A1 Akeel A. Yasseen
A1 Thekra A. Al-Musawi
YR 2001
UL http://nsj.org.sa/content/6/4/233.abstract
AB OBJECTIVE: The metaphase of 21 severely mentally retarded patients were studies to assess the role of satellite association in the etiology of mental retardation.METHODS: Peripheral blood culture, chromosome harvesting and study scoring were conducted according to standard methods.RESULTS: Considered as a whole the results indicate that there is a significant increase in the frequency of satellite association among the mentally retarded.CONCLUSION: The present study concluded that satellite association may play a role in the etiology of mental retardation and may explain to some extent the presence of normal karyotype in some mental retardation patients.