RT Journal Article SR Electronic T1 Pathophysiology of carpal tunnel syndrome JF Neurosciences Journal JO Neurosciences (Riyadh) FD Prince Sultan Military Medical City SP 04 OP 09 VO 20 IS 1 A1 Aboonq, Moutasem S. YR 2015 UL http://nsj.org.sa/content/20/1/04.abstract AB Carpal tunnel syndrome (CTS) is the most common median nerve neuropathy, accounting for 90% of all neuropathies. Carpal tunnel syndrome presents in 3.8% of the general population, with a higher prevalence among women. There are several risk factors associated with CTS, including both medical and non medical factors. The pathophysiologic mechanisms involved in the median nerve compression and traction are thought to be complex, and as yet are not fully understood. The present review aimed to provide an overview of the pathophysiology of median nerve neuropathy in the carpal tunnel, and subsequent development of CTS.