PT - JOURNAL ARTICLE AU - Hassan M. Ismail AU - Abdulsalam A. Al-Sulaiman AU - Alaeddin A. Abolenin AU - Shoaa Al-Shammary AU - Fahd Al-Khamis AU - Khalid Al-Qulaiti AU - Mahdi S. Abumadini TI - Newly diagnosed seizures in adults DP - 2003 Apr 01 TA - Neurosciences Journal PG - 104--106 VI - 8 IP - 2 4099 - http://nsj.org.sa/content/8/2/104.short 4100 - http://nsj.org.sa/content/8/2/104.full SO - Neurosciences (Riyadh)2003 Apr 01; 8 AB - OBJECTIVE: To study the clinical, electroencephalographic (EEG) and computed tomography (CT) profile in a hospital population of over 18-years adult patients with newly diagnosed recurrent seizures.METHODS: The clinical profiles obtained from history including detailed description of the seizures, examination, EEG and CT findings were recorded prospectively for all over-18 patients who were referred to the electrodiagnostic service at King Fahd Hospital of the University, Al-Khobar, Eastern Province, Kingdom of Saudi Arabia from January 1, 1996 to December 31, 1997. The data was entered into a standard database file and analyzed using a personal computer.RESULTS: Seventy-three patients (43 males, 30 females, mean age 32.3 years) with newly diagnosed recurrent seizures were studied. A positive family history of seizures was found in 12.3%. The main seizure types were partial in 27 (37%), partial with secondary generalization in 22 (30.1%) and generalized in 24 (32.9%). The types of epileptic syndromes included localization-related 34 (46.6%), generalized 24 (32.9%) and undetermined 15 (20.5%). The EEG was abnormal in 45 (61.6%) with epileptiform activity, focal in 22 (48.9%), generalized in 11 (24.4%) and non-epileptiform activity in 12 (26.7%). The cranial CT findings were normal in 44 patients (60.3%) and abnormal in 29 (39.7%) patients, with focal lesions in 19 (65.5%) and generalized cerebral atrophy in 10 (34.5%).CONCLUSION: Our results showed that partial and partial with secondary generalization seizures are the most frequent seizure type and the most common epileptic syndrome was the localization-related type in this age group. These results are comparable to previous population- and hospital-based western reports.