PT - JOURNAL ARTICLE AU - Jamjoom, Bakur A. AU - Jamjoom, Abdulhakim B. TI - Timing of long bone fracture fixation in severe traumatic brain injury DP - 2012 Apr 01 TA - Neurosciences Journal PG - 111--114 VI - 17 IP - 2 4099 - http://nsj.org.sa/content/17/2/111.short 4100 - http://nsj.org.sa/content/17/2/111.full SO - Neurosciences (Riyadh)2012 Apr 01; 17 AB - We present a review of the published evidence on the optimal timing for long bone fracture fixation in severe traumatic brain injury (TBI); a matter that remains under debate. Fifteen retrospective articles (level II-3 evidence) were considered suitable for the review. We conclude that the published evidence does not provide a definitive answer to the optimal timing of long bone fracture surgery in severe TBI, and a randomized controlled trial is required. We recommend a safe strategy that combines damage control surgery with a period of monitoring of intracranial pressure, cerebral perfusion pressure, and if available brain tissue oxygen until the patient is considered fit for the fracture fixation.