RT Journal Article SR Electronic T1 Timing of long bone fracture fixation in severe traumatic brain injury JF Neurosciences Journal JO Neurosciences (Riyadh) FD Prince Sultan Military Medical City SP 111 OP 114 VO 17 IS 2 A1 Jamjoom, Bakur A. A1 Jamjoom, Abdulhakim B. YR 2012 UL http://nsj.org.sa/content/17/2/111.abstract AB We present a review of the published evidence on the optimal timing for long bone fracture fixation in severe traumatic brain injury (TBI); a matter that remains under debate. Fifteen retrospective articles (level II-3 evidence) were considered suitable for the review. We conclude that the published evidence does not provide a definitive answer to the optimal timing of long bone fracture surgery in severe TBI, and a randomized controlled trial is required. We recommend a safe strategy that combines damage control surgery with a period of monitoring of intracranial pressure, cerebral perfusion pressure, and if available brain tissue oxygen until the patient is considered fit for the fracture fixation.