RT Journal Article SR Electronic T1 Risk of seizure recurrences after first unprovoked seizure during childhood JF Neurosciences Journal JO Neurosciences (Riyadh) FD Prince Sultan Military Medical City SP 95 OP 98 VO 6 IS 2 A1 Mohammed S. Bessisso A1 Mahmoud F. El-Said A1 Naema A. Almula A1 Sameer B. Azzam A1 Hani A. Sweid A1 Mariam G. Al-Ali YR 2001 UL http://nsj.org.sa/content/6/2/95.abstract AB OBJECTIVE: To find out incidence of seizure recurrence and its risk factor after the first unprovoked attack in children below 12 years of age.METHODS: A prospective study was carried out between 30th April 1996 - 1st May 1997 with the aim to find out the incidence of seizure recurrence and its risk factor after the first unprovoked attack in children below 12 years of age. All patients aged between 2 months - 12 years who presented with first unprovoked seizure at Hamad General Hospital, Doha, Qatar were studied. Seizures due to fever, metabolic causes, post-traumatic,and myoclonic seizures, infantile spasms, absence epilepsy and pseudo-seizures were excluded. All patients were followed for a minimum of one year. Possible risk factors such as sex, age, family history of epilepsy, delayed development, focal onset, clustered onset (two or more attacks within 24 hours), abnormal neurological findings and epileptogenic activity of electroencephalography were considered. RESULTS: There was a total of 33 patients (14 male and 19 female), 11 patients (33%) had recurrence. Significant risk factors for seizure recurrence were abnormal encephalograms (p=0.009), positive family history (p=0.03) and cluster onset (p=0.04). Presence of one or more risk factor (p=0.01) was significant. The other risk factors were not statistically significant.CONCLUSION: The incidence of seizure recurrence is higher in-patients who have one or more risk factors. The patient and the family should be aware about possibility seizure recurrence and should be involved in the decision of starting treatment after first attack.