RT Journal Article
SR Electronic
T1 Central fever due to hypothalamic lesion in a patient with tuberculous meningitis
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 301
OP 303
VO 7
IS 4
A1 Abdulrahman M. Alshahrani
A1 Yousef A. Al-Said
A1 Irfan A. Mamoun
A1 Leopold J. Streletz
YR 2002
UL http://nsj.org.sa/content/7/4/301.abstract
AB Abnormalities of body temperature are perhaps the most common features in many systemic pathologic processes. Such pathologic alterations are nearly always the result of extrinsic factors (for example, systemic pyrogens) which affect the hypothalamic thermoregulatory center by way of circulatory system. Much less common is alterations in temperature regulation resulting from intrinsic lesions of the thermoregulatory center in the hypothalamus. We report a patient with tuberculous meningitis who continued to have persistent fever despite the satisfactory treatment of her tuberculosis. A central thermoregulatory defect was documented and was attributed to a small structural lesion in the anterior hypothalamus.