PT  - JOURNAL ARTICLE
AU  - Varghese, Thomas
AU  - Ahmed, Riaz
AU  - Sankaran, Jayaram D.
AU  - Al-Khusaiby, Saleh M.
TI  - D-Penicillamine induced myasthenia gravis
DP  - 2002 Oct 01
TA  - Neurosciences Journal
PG  - 293--295
VI  - 7
IP  - 4
4099  - http://nsj.org.sa/content/7/4/293.short
4100  - http://nsj.org.sa/content/7/4/293.full
SO  - Neurosciences (Riyadh)2002 Oct 01; 7
AB  - Myasthenia gravis is a disorder of impaired neuromuscular transmission resulting in weakness and abnormal fatigability on exertion, improved by anti-acetyl cholinesterase drugs. A number of drugs are known to exacerbate myasthenia gravis or interfere with neuromuscular transmission. We report a case of D-penicillamine induced myasthenia gravis who developed ptosis, diplopia and easy fatigability, 4 years after initiation of the drug for Wilson’s disease. On stopping the drug, within 3 months all her symptoms disappeared without any anti-acetyl cholinesterase drugs. Thus, the onset of drug induced myasthenia gravis could be insidious but the withdrawal of the drug leads to rapid recovery.