RT Journal Article
SR Electronic
T1 D-Penicillamine induced myasthenia gravis
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 293
OP 295
VO 7
IS 4
A1 Thomas Varghese
A1 Riaz Ahmed
A1 Jayaram D. Sankaran
A1 Saleh M. Al-Khusaiby
YR 2002
UL http://nsj.org.sa/content/7/4/293.abstract
AB Myasthenia gravis is a disorder of impaired neuromuscular transmission resulting in weakness and abnormal fatigability on exertion, improved by anti-acetyl cholinesterase drugs. A number of drugs are known to exacerbate myasthenia gravis or interfere with neuromuscular transmission. We report a case of D-penicillamine induced myasthenia gravis who developed ptosis, diplopia and easy fatigability, 4 years after initiation of the drug for Wilson’s disease. On stopping the drug, within 3 months all her symptoms disappeared without any anti-acetyl cholinesterase drugs. Thus, the onset of drug induced myasthenia gravis could be insidious but the withdrawal of the drug leads to rapid recovery.