RT Journal Article
SR Electronic
T1 The effects of acupuncture on rats with brain ischemia-reperfusion
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 10
OP 13
VO 14
IS 1
A1 Kavakli, Ahmet
A1 Kose, Evren
A1 Akpolat, Nusret
A1 Sarsilmaz, Mustafa
YR 2009
UL http://nsj.org.sa/content/14/1/10.abstract
AB OBJECTIVE: To investigate the damage of brain ischemia-reperfusion (I/R) caused by occlusion of the middle cerebral artery (MCA), and the effects of acupuncture on this damage.METHODS: This investigation took place in the Experimental Research Unit of Firat University, Elazig, Turkey in January-February 2007. For this aim, 14 rats were divided into 2 groups: I/R (control) and I/R+acupuncture (experiment). In the I/R group, the MCA was occluded for 60 minutes, after this reperfusion was applied. In the I/R+acupuncture group, dry needle acupuncture was applied after reperfusion for 10 days. At the end of the experiment, all rats were sacrificed. The brain tissues were examined after staining with hematoxylin and eosin.RESULTS: In the samples belonging to the I/R group, widespread necrotic areas, red neurons, vacuolization, congestion, and edema were observed. In the I/R+ acupuncture group, the findings of ischemia were significantly decreased when compared with the I/R group.CONCLUSION: The damage caused by I/R was decreased by manual acupuncture therapy, however, further clinical studies are needed to determine the mechanism of acupuncture treatment, the optimal timing, and duration of acupuncture treatment in such disorders.