PT - JOURNAL ARTICLE AU - Abdulrahman A. Al-Atram TI - A review of the bidirectional relationship between psychiatric disorders and diabetes mellitus AID - 10.17712/nsj.2018.2.20170132 DP - 2018 Apr 01 TA - Neurosciences Journal PG - 91--96 VI - 23 IP - 2 4099 - http://nsj.org.sa/content/23/2/91.short 4100 - http://nsj.org.sa/content/23/2/91.full SO - Neurosciences (Riyadh)2018 Apr 01; 23 AB - The prevalence of type 2 diabetes is rising worldwide, including Saudi Arabia. Among patients with diabetes, 30% suffer from mental disorders, such as depression, schizophrenia, delirium, and substance misuse (for example, tobacco smoking). Moreover, these disorders appear to share a bidirectional relationship with diabetes. For example, the incidence of diabetes has been shown to be 2-4 times greater in patients with schizophrenia than in normal individuals; also, there is a known association between depression and diabetes. In this review, we focus specifically on the bidirectional relationship between diabetes and psychiatric disorders, including the effects of antipsychotic drugs.