RT Journal Article SR Electronic T1 A review of the bidirectional relationship between psychiatric disorders and diabetes mellitus JF Neurosciences Journal JO Neurosciences (Riyadh) FD Prince Sultan Military Medical City SP 91 OP 96 DO 10.17712/nsj.2018.2.20170132 VO 23 IS 2 A1 Abdulrahman A. Al-Atram YR 2018 UL http://nsj.org.sa/content/23/2/91.abstract AB The prevalence of type 2 diabetes is rising worldwide, including Saudi Arabia. Among patients with diabetes, 30% suffer from mental disorders, such as depression, schizophrenia, delirium, and substance misuse (for example, tobacco smoking). Moreover, these disorders appear to share a bidirectional relationship with diabetes. For example, the incidence of diabetes has been shown to be 2-4 times greater in patients with schizophrenia than in normal individuals; also, there is a known association between depression and diabetes. In this review, we focus specifically on the bidirectional relationship between diabetes and psychiatric disorders, including the effects of antipsychotic drugs.