PT  - JOURNAL ARTICLE
AU  - Kurdi, Maher E.
AU  - Chamsi-Pasha, Mohammed A.
AU  - Baeesa, Saleh S.
AU  - Jan, Mohammed M.
TI  - Dandy Walker malformation and hypertrophic cardiomyopathy. Unusual fatal association
DP  - 2009 Oct 01
TA  - Neurosciences Journal
PG  - 368--370
VI  - 14
IP  - 4
4099  - http://nsj.org.sa/content/14/4/368.short
4100  - http://nsj.org.sa/content/14/4/368.full
SO  - Neurosciences (Riyadh)2009 Oct 01; 14
AB  - Dandy Walker malformation (DWM) is a rare congenital brain anomaly characterized by cystic dilation of the fourth ventricle and hypoplasia of the cerebellar vermis. Other extracranial anomalies can be associated, including cardiac defects. We report a rare patient with DWM associated with progressive heart failure secondary to hypertrophic cardiomyopathy. He was diagnosed at 2 months of age and died 5 months later. We conclude that hypertrophic cardiomyopathy can be associated with DWM with poor prognosis. A careful cardiac evaluation is needed in all infants with DWM for early recognition of such potentially serious associated cardiac malformations.