RT Journal Article
SR Electronic
T1 Dandy Walker malformation and hypertrophic cardiomyopathy. Unusual fatal association
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 368
OP 370
VO 14
IS 4
A1 Kurdi, Maher E.
A1 Chamsi-Pasha, Mohammed A.
A1 Baeesa, Saleh S.
A1 Jan, Mohammed M.
YR 2009
UL http://nsj.org.sa/content/14/4/368.abstract
AB Dandy Walker malformation (DWM) is a rare congenital brain anomaly characterized by cystic dilation of the fourth ventricle and hypoplasia of the cerebellar vermis. Other extracranial anomalies can be associated, including cardiac defects. We report a rare patient with DWM associated with progressive heart failure secondary to hypertrophic cardiomyopathy. He was diagnosed at 2 months of age and died 5 months later. We conclude that hypertrophic cardiomyopathy can be associated with DWM with poor prognosis. A careful cardiac evaluation is needed in all infants with DWM for early recognition of such potentially serious associated cardiac malformations.