PT  - JOURNAL ARTICLE
AU  - Tohid, Hassaan
AU  - Faizan, Muhammad
AU  - Faizan, Uzma
TI  - Alterations of the occipital lobe in schizophrenia
AID  - 10.17712/nsj.2015.3.20140757
DP  - 2015 Jul 01
TA  - Neurosciences Journal
PG  - 213--224
VI  - 20
IP  - 3
4099  - http://nsj.org.sa/content/20/3/213.short
4100  - http://nsj.org.sa/content/20/3/213.full
SO  - Neurosciences (Riyadh)2015 Jul 01; 20
AB  - The relationship of the occipital lobe of the brain with schizophrenia is not commonly studied; however, this topic is considered an essential subject matter among clinicians and scientists. We conducted this systematic review to elaborate the relationship in depth. We found that most schizophrenic patients show normal occipital anatomy and physiology, a minority showed dwindled values, and some demonstrated augmented function and structure. The findings are laborious to incorporate within single disease models that present the involvement of the occipital lobe in schizophrenia. Schizophrenia progresses clinically in the mid-twenties and thirties and its prognosis is inadequate. Changes in the volume, the gray matter, and the white matter in the occipital lobe are quite evident; however, the mechanism behind this involvement is not yet fully understood. Therefore, we recommend further research to explore the occipital lobe functions and volumes across the different stages of schizophrenia.