RT Journal Article SR Electronic T1 Alterations of the occipital lobe in schizophrenia JF Neurosciences Journal JO Neurosciences (Riyadh) FD Prince Sultan Military Medical City SP 213 OP 224 DO 10.17712/nsj.2015.3.20140757 VO 20 IS 3 A1 Tohid, Hassaan A1 Faizan, Muhammad A1 Faizan, Uzma YR 2015 UL http://nsj.org.sa/content/20/3/213.abstract AB The relationship of the occipital lobe of the brain with schizophrenia is not commonly studied; however, this topic is considered an essential subject matter among clinicians and scientists. We conducted this systematic review to elaborate the relationship in depth. We found that most schizophrenic patients show normal occipital anatomy and physiology, a minority showed dwindled values, and some demonstrated augmented function and structure. The findings are laborious to incorporate within single disease models that present the involvement of the occipital lobe in schizophrenia. Schizophrenia progresses clinically in the mid-twenties and thirties and its prognosis is inadequate. Changes in the volume, the gray matter, and the white matter in the occipital lobe are quite evident; however, the mechanism behind this involvement is not yet fully understood. Therefore, we recommend further research to explore the occipital lobe functions and volumes across the different stages of schizophrenia.