PT  - JOURNAL ARTICLE
AU  - Daoud, Emna
AU  - Chabchoub, Imen
AU  - Neji, Henda
AU  - Toumi, Nozha
AU  - Abdallah, Rim B.
AU  - Aloulou, Hajer
AU  - Kammoun, Fatma
AU  - Mahfoudh, Abdelmajid
AU  - Hachicha, Mongia
AU  - Mnif, Jamel
AU  - Mahfoudh, Kheireddine B.
AU  - Mnif, Zeineb
TI  - How MRI can contribute to the diagnosis of acute demyelinating encephalomyelitis in children
DP  - 2011 Apr 01
TA  - Neurosciences Journal
PG  - 137--145
VI  - 16
IP  - 2
4099  - http://nsj.org.sa/content/16/2/137.short
4100  - http://nsj.org.sa/content/16/2/137.full
SO  - Neurosciences (Riyadh)2011 Apr 01; 16
AB  - OBJECTIVE: To illustrate through 10 pediatric cases, the clinical features, course, and importance of neuroimaging (especially MRI) in guiding the diagnosis of acute disseminated encephalomyelitis (ADEM) and controlling patients after treatment.METHODS: A retrospective review of 10 pediatric cases of ADEM, with special regard to the MRI features, presenting to the Pediatric Departments, Hedi Chaker Hospital, Sfax, Tunisia between January 2002 and December 2008.RESULTS: Children with ADEM presented with variable and multiple neurological signs most often occurring after an infectious episode, especially after upper respiratory tract infection. The MRI permitted confirmation of the diagnosis by showing demyelinating lesions either in the brainstem, the cerebellum, the cerebral white and grey matter, or in the spine of all patients.CONCLUSION: Acute disseminated encephalomyelitis is characterized by multifocal demyelinating lesions resulting in varied neurological signs. The MRI is the technique of choice to show these lesions.