RT Journal Article SR Electronic T1 How MRI can contribute to the diagnosis of acute demyelinating encephalomyelitis in children JF Neurosciences Journal JO Neurosciences (Riyadh) FD Prince Sultan Military Medical City SP 137 OP 145 VO 16 IS 2 A1 Daoud, Emna A1 Chabchoub, Imen A1 Neji, Henda A1 Toumi, Nozha A1 Abdallah, Rim B. A1 Aloulou, Hajer A1 Kammoun, Fatma A1 Mahfoudh, Abdelmajid A1 Hachicha, Mongia A1 Mnif, Jamel A1 Mahfoudh, Kheireddine B. A1 Mnif, Zeineb YR 2011 UL http://nsj.org.sa/content/16/2/137.abstract AB OBJECTIVE: To illustrate through 10 pediatric cases, the clinical features, course, and importance of neuroimaging (especially MRI) in guiding the diagnosis of acute disseminated encephalomyelitis (ADEM) and controlling patients after treatment.METHODS: A retrospective review of 10 pediatric cases of ADEM, with special regard to the MRI features, presenting to the Pediatric Departments, Hedi Chaker Hospital, Sfax, Tunisia between January 2002 and December 2008.RESULTS: Children with ADEM presented with variable and multiple neurological signs most often occurring after an infectious episode, especially after upper respiratory tract infection. The MRI permitted confirmation of the diagnosis by showing demyelinating lesions either in the brainstem, the cerebellum, the cerebral white and grey matter, or in the spine of all patients.CONCLUSION: Acute disseminated encephalomyelitis is characterized by multifocal demyelinating lesions resulting in varied neurological signs. The MRI is the technique of choice to show these lesions.