RT Journal Article SR Electronic T1 Down syndrome presenting with multiple sclerosis, thyroid dysfunction, and diabetes mellitus. <i>Multiple autoimmune disorders in a genetic disorder</i> JF Neurosciences Journal JO Neurosciences (Riyadh) FD Prince Sultan Military Medical City SP 375 OP 377 VO 16 IS 4 A1 Sayed M. Nabavi A1 Ali Hamzehloo A1 Zari Sabet YR 2011 UL http://nsj.org.sa/content/16/4/375.abstract AB Down syndrome (DS) is one of the most common survivable chromosomal disorders, and is well known to be associated with multiple autoimmune diseases. Multiple sclerosis (MS) is a chronic inflammatory autoimmune demyelinating disease of the central nervous system. An association of DS and other autoimmune disease has been previously reported, and we report one case of DS in coexistence with MS, diabetes mellitus, and thyroid diseases. We suggest thatMS, such as other autoimmune diseases, is prevalent in DS patients.