PT  - JOURNAL ARTICLE
AU  - Qiu, Tianlun
AU  - Jin, Guoliang
AU  - Bao, Wuqiao
TI  - The interrelated effects of 2D angiographic morphological variables and aneurysm rupture
DP  - 2014 Jul 01
TA  - Neurosciences Journal
PG  - 210--217
VI  - 19
IP  - 3
4099  - http://nsj.org.sa/content/19/3/210.short
4100  - http://nsj.org.sa/content/19/3/210.full
SO  - Neurosciences (Riyadh)2014 Jul 01; 19
AB  - Objective: To investigate the correlations between morphological parameters and rupture status in cerebral aneurysm patients.Methods: We conducted a retrospective study of 34 patient records from March 2010 to December 2012. The morphological parameters of 34 ruptured and 42 unruptured cerebral aneurysms in 34 patients (males: female, 15:19; mean age 55.79±10.64 years) leading to subarachnoid hemorrhage were examined using 3D (dimension) digital subtraction angiography (DSA) models, to identify the correlation between 2D morphological parameters and risk factors of rupture status with univariate and multivariate analysis.Results: The 2D morphological parameters in ruptured aneurysms were significantly different from those observed in unruptured aneurysms (p<0.05), though only size and height-width ratios independently predicted rupture status. Dmax, Hmax, bottleneck factor, and size ratio significantly correlated with height-width ratio in ruptured but not unruptured aneurysms.Conclusions: A specific set of morphological characteristics, most notably size and height-width ratios, may help to understand rupture risk by indicating arterial stretch character in cerebral aneurysms patients.