PT - JOURNAL ARTICLE AU - Aydın Cagac TI - Farming, well water consumption, rural living, and pesticide exposure in early life as the risk factors for Parkinson disease in Iğdır province AID - 10.17712/nsj.2020.2.20190104 DP - 2020 Apr 01 TA - Neurosciences Journal PG - 129--135 VI - 25 IP - 2 4099 - http://nsj.org.sa/content/25/2/129.short 4100 - http://nsj.org.sa/content/25/2/129.full SO - Neurosciences (Riyadh)2020 Apr 01; 25 AB - Objectives: To investigate potential risk factors for Parkinson’s disease (PD) in elderly individuals rural living in Turkey.Methods: In total, 72 consecutive elderly Parkinson disease patients referred to the Neurology Clinic, Iğdir State Hospital, Iğdır, Turkey were included in the study. A structured questionnaire comprising questions on history of pastoral living, pit water consumption, and exposure to ionizing radiation and pesticides was administered to the patients. The patients were divided into 2 groups on the basis of water consumption: well water consumption group and city network consumption group.Results: Of 72 patients with PD, 49 (68.1%) exposed to well water while 23 (31.9%) did not exposed to well water. The average duration of well water consumption was 20 (standard deviation 6) years (p<0.01) in group 1. Nitrate, sulfate and heavy metal levels were significantly higher in well water than in city network water (p<0.05).Conclusion: Consumption of well water containing heavy metals and nitrates in early life may contribute to the etiology of Parkinson disease in elderly individuals in Iğdır province of Turkey