RT Journal Article
SR Electronic
T1 Right-Sided clinical findings are worse prognostic factor in Multiple Sclerosis patients?
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 97
OP 103
DO 10.17712/nsj.2020.2.20190111
VO 25
IS 2
A1 Asuman O. Varoglu
A1 Ece Balkuv
YR 2020
UL http://nsj.org.sa/content/25/2/97.abstract
AB Objectives: To investigate the importance of the side of clinical findings in predicting the prognosis in multiple sclerosis (MS) patients.Methods: In our study we enrolled 361 MS patients. This study as retrospective was performed. On neurological examinations, clinical findings were recorded as right, left and bilateral. We used the Expanded Disability Status Scale (EDSS), Multiple Sclerosis Severity Score (MSSS), Progression Index (PI) for neurological status.Results: At the first attack, there were differences in the EDSS, PI and MSSS of right-sided findings between remission and attack periods (p=0.057, p=0.008, p=0.017 respectively). In the right-sided clinical findings, the value of PI and MSSS were higher than the others between in remission and attack periods (p=0.002, p=0.045 respectively). At last attack, we found statically differences in EDSS, MSSS values between remission and attack periods in only right-sided clinical findings (p=0.042, p=0.027 respectively). In the first presentation the PI value in bilateral clinical signs was lower (p=0.016).Conclusion: Right-sided clinical findings were poor prognostic factors in all stages of MS, whereas bilateral findings were not poor prognostic factor in the early-stage MS.