PT  - JOURNAL ARTICLE
AU  - Amro F. Al-Habib
AU  - Hissah Al Abdulsalam
AU  - Jehad Ahmed
AU  - Fahad Albadr
AU  - Wajda Alhothali
AU  - Abdullah Alzahrani
AU  - Abdullah Abojamea
AU  - Abdullah Altowim
AU  - Anhar Ullah
AU  - Metab Alkubeyyer
TI  - Association between craniovertebral junction abnormalities and syringomyelia in patients with chiari malformation type-1
AID  - 10.17712/nsj.2020.4.20200008
DP  - 2020 Aug 01
TA  - Neurosciences Journal
PG  - 308--315
VI  - 25
IP  - 4
4099  - http://nsj.org.sa/content/25/4/308.short
4100  - http://nsj.org.sa/content/25/4/308.full
SO  - Neurosciences (Riyadh)2020 Aug 01; 25
AB  - Objectives: To assess the correlation between craniovertebral junction (CVJ) abnormalities and syringomyelia in patients with Chiari malformation type-1 (CM1).Methods: This was a retrospective study including patients with CM1. Identification of cases was done by searching a radiology database at a university hospital from 2012 to 2017. Patients were divided into 2 groups based on whether CVJ abnormalities were present (CVJ+) or absent (CVJ-). The patients’ demographic and clinical data were reviewed. All magnetic resonance imaging studies were examined by a certified neuroradiologist.Results: Sixty-four consecutive patients with CM1 were included. The mean age was 24±17 years; 59% were females. The CVJ+ group had more female patients (p = 0.012). The most frequent CVJ abnormality was platybasia (71%), followed by short clivus (44%) and cervical kyphosis (33%). The CVJ abnormalities were more in Syringomyelia cases (p = 0.045). However, the results were not significant when hydrocephalus cases were excluded.Conclusion: Among CM1 patients, CVJ abnormalities were found more in patients with syringomyelia. Future studies with larger sample size are required to further study the correlation between CVJ abnormalities and both syringomyelia and hydrocephalus in CM1 patients.