RT Journal Article
SR Electronic
T1 Association between craniovertebral junction abnormalities and syringomyelia in patients with chiari malformation type-1
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 308
OP 315
DO 10.17712/nsj.2020.4.20200008
VO 25
IS 4
A1 Al-Habib, Amro F.
A1 Al Abdulsalam, Hissah
A1 Ahmed, Jehad
A1 Albadr, Fahad
A1 Alhothali, Wajda
A1 Alzahrani, Abdullah
A1 Abojamea, Abdullah
A1 Altowim, Abdullah
A1 Ullah, Anhar
A1 Alkubeyyer, Metab
YR 2020
UL http://nsj.org.sa/content/25/4/308.abstract
AB Objectives: To assess the correlation between craniovertebral junction (CVJ) abnormalities and syringomyelia in patients with Chiari malformation type-1 (CM1).Methods: This was a retrospective study including patients with CM1. Identification of cases was done by searching a radiology database at a university hospital from 2012 to 2017. Patients were divided into 2 groups based on whether CVJ abnormalities were present (CVJ+) or absent (CVJ-). The patients’ demographic and clinical data were reviewed. All magnetic resonance imaging studies were examined by a certified neuroradiologist.Results: Sixty-four consecutive patients with CM1 were included. The mean age was 24±17 years; 59% were females. The CVJ+ group had more female patients (p = 0.012). The most frequent CVJ abnormality was platybasia (71%), followed by short clivus (44%) and cervical kyphosis (33%). The CVJ abnormalities were more in Syringomyelia cases (p = 0.045). However, the results were not significant when hydrocephalus cases were excluded.Conclusion: Among CM1 patients, CVJ abnormalities were found more in patients with syringomyelia. Future studies with larger sample size are required to further study the correlation between CVJ abnormalities and both syringomyelia and hydrocephalus in CM1 patients.