RT Journal Article
SR Electronic
T1 Predicting future handedness and hemispheric dominance during infancy by analyzing sleep spindles
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 188
OP 192
DO 10.17712/nsj.2020.3.20190129
VO 25
IS 3
A1 Alwadei, Ali H.
A1 AlOsaimi, Turki F.
A1 Bayounis, Manar A.
A1 AlHajaj, Ghadd A
A1 Bashiri, Fahad A.
YR 2020
UL http://nsj.org.sa/content/25/3/188.abstract
AB Objectives: To investigate whether sleep spindles asynchrony (SSA) using scalp sleep electroencephalogram (EEG) among children below 2 years of age can predict future handedness.Methods: This is a retrospective study conducted from October 2016 until June 2017 at the King Fahad Medical City (KFMC), Riyadh, Kingdom of Saudi Arabia. We retrospectively reviewed 300 EEGs recorded at our neurophysiology laboratory.We included EEGs performed during sleep for infants aged 2 months to 2 years who have already attained their handedness or those aged above 2 years. We excluded records of children younger than 2 months or above 2 years of age (at the time of the EEG) or those aged below 2 years (at the time of the interview), and severely abnormal tracings and those without sleep or enough SSA .Results: The lateralization of Sleep Spindles (SS) was mostly right-hemispheric (52%) compared to left-hemispheric (36.4%). The overall SS laterality did not correlate with handedness (p=0.81). In the majority of right-handed (64%) and left-handed (60%) children, the SSA was contralateral to the side of hand preference; however, it did not correlate statistically (p=0.377).Conclusion: We were unable to prove a statistically significant correlation between SSA and future hand preference. Further research involving larger cohorts is still needed.