TY - JOUR T1 - Posterior mediastinal neuroblastoma masked as flaccid paraparesis in a 3 year child JF - Neurosciences Journal JO - Neurosciences (Riyadh) SP - 320 LP - 323 DO - 10.17712/nsj.2019.4.20190036 VL - 24 IS - 4 AU - Farah S. Yahya AU - Hieder A. Al-Shami Y1 - 2019/10/01 UR - http://nsj.org.sa/content/24/4/320.abstract N2 - Neuroblastoma is an embryonic tumor of the sympathetic nervous system originating from neural crest cell remnants, which may be found in the adrenal glands or sympathetic chain. We report a case of a three-year-old girl who presented with flaccid paraparesis, and acute respiratory distress that required mechanical ventilation after a multiple-day history of gradual-onset dyspnea and right upper-lung opacity that was initially misdiagnosed as pneumonia. Chest and spinal magnetic resonance imaging (MRI) revealed a tumor in the posterior mediastinum with intra-spinal canal extension. The patient underwent thoracotomy and surgical en bloc resection with spinal canal decompression. Histopathology revealed neuroblastoma. The postoperative period was uneventful. The patient was administered a course of chemotherapy but died due to advanced stage tumor, severe pancytopenia, and septicemia with renal failure. The aim of this report is to consider posterior mediastinal neuroblastoma in the differential diagnosis of dyspnea and acute lower limb weakness in young children. ER -