PT  - JOURNAL ARTICLE
AU  - Shaheen, Misealreem A.
AU  - Albelali, Areej A.
AU  - AlKanhal, Raghad M.
AU  - AlSaqabi, Muneera K.
AU  - AlTurki, Raghad M.
AU  - AlAskar, Raghad S.
AU  - Khan, Altaf H.
AU  - Khatri, Ismail A.
TI  - Frequency, risk factors, and outcomes in patients with significant carotid artery disease admitted to King Abdulaziz Medical City, Riyadh with Ischemic Stroke
AID  - 10.17712/nsj.2018.4.20190046
DP  - 2019 Oct 01
TA  - Neurosciences Journal
PG  - 264--268
VI  - 24
IP  - 4
4099  - http://nsj.org.sa/content/24/4/264.short
4100  - http://nsj.org.sa/content/24/4/264.full
SO  - Neurosciences (Riyadh)2019 Oct 01; 24
AB  - Objectives: To determine the frequency, risk factors, and outcomes of significant carotid artery disease (CAD) in patients with ischemic stroke.Methods: The frequency of significant CAD in patients admitted to the Stroke Unit between January 2014 and December 2015 was determined from radiological data. Outcomes were determined clinically and radiologically.Results: Among 435 patients, 273 were men (62.8%), with a mean age of 57.4±12.2 years. Significant CAD was found in 48 vessels in 40 (9.2%) patients, of which 30 patients were symptomatic. Nine of these patients were treated with carotid artery stenting, one underwent carotid endarterectomy, and 3 underwent an urgent thrombectomy, without stenting. Seventeen symptomatic patients were not treated for the following reasons: patient/family refusal (n=2), contraindications (n=5), and complete occlusion (n=10). One (7.7%) of the 13 treated patients had an ipsilateral stroke on follow up, one (7.7%) had contralateral transient ischemic attack (TIA), 9 (69.2%) had no recurrence, and no clinical data were available for 2 patients. Among the 17 untreated patients, one (5.9%) had an ipsilateral stroke, 7 (41.2%) had no recurrence, and 9 (52.9%) were lost to follow up.Conclusion: Significant carotid artery disease is uncommon in our cohort found in less than 10% of patients. Vascular risk factors are more or less similar between patients with or without CAD except obesity which appears to have inverse relation with CAD. A small number of patients received carotid intervention with no recurrence of stroke at limited follow up.