RT Journal Article
SR Electronic
T1 Tardive dyskinesia occurring in a young woman after withdrawal of an atypical antipsychotic drug
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 376
OP 379
DO 10.17712/nsj.2015.4.20150078
VO 20
IS 4
A1 Alblowi, Mohammed A.
A1 Alosaimi, Fahad D.
YR 2015
UL http://nsj.org.sa/content/20/4/376.abstract
AB Tardive dyskinesia (TD) is one of the most serious and disturbing side-effects of dopamine receptor antagonists. It affects 20-50% of patients on long-term antipsychotic therapy. The pathophysiology of TD remains poorly understood, and treatment is often challenging. Here, we present a 32-year-old woman presenting with a 9-month history of TD occurring after risperidone withdrawal, and characterized almost exclusively by tongue protrusion. After being seen by different specialties and undergoing multiple investigations, she was eventually correctly diagnosed with TD by a specialist team and successfully treated with amantadine. Vigilance and awareness of this condition and its risk factors are required to make the correct diagnosis, especially in cases with unusual presentations caused by atypical antipsychotics, and treatment can be challenging.