PT - JOURNAL ARTICLE AU - Sonbaa, Ali M. AU - Khayat, Alaa F. AU - Almekhlafi, Mohammed A. TI - Safety of tissue plasminogen activator factor in an acute stroke patient with two unruptured cerebral aneurysms AID - 10.17712/nsj.2018.4.20180054 DP - 2018 Oct 01 TA - Neurosciences Journal PG - 334--337 VI - 23 IP - 4 4099 - http://nsj.org.sa/content/23/4/334.short 4100 - http://nsj.org.sa/content/23/4/334.full SO - Neurosciences (Riyadh)2018 Oct 01; 23 AB - It is estimated that 6.6%-9.3% of stroke patients have unruptured cerebral aneurysms. The safety of recombinant tissue plasminogen activator (r-tPA) for stroke patients with these aneurysms is uncertain. We report the case of a 58-year old male presented with an acute ischemic stroke within 2 hours of symptom onset and was treated with r-tPA. Further investigation showed that the patient had 2 unruptured cerebral aneurysms. He recovered completely from the stroke and was discharged home in a few days with no deficits. Although cerebral aneurysms are considered a relative contraindication for r-tPA, our case provides evidence that it can be safely administered to these patients.