RT Journal Article SR Electronic T1 Safety of tissue plasminogen activator factor in an acute stroke patient with two unruptured cerebral aneurysms JF Neurosciences Journal JO Neurosciences (Riyadh) FD Prince Sultan Military Medical City SP 334 OP 337 DO 10.17712/nsj.2018.4.20180054 VO 23 IS 4 A1 Ali M. Sonbaa A1 Alaa F. Khayat A1 Mohammed A. Almekhlafi YR 2018 UL http://nsj.org.sa/content/23/4/334.abstract AB It is estimated that 6.6%-9.3% of stroke patients have unruptured cerebral aneurysms. The safety of recombinant tissue plasminogen activator (r-tPA) for stroke patients with these aneurysms is uncertain. We report the case of a 58-year old male presented with an acute ischemic stroke within 2 hours of symptom onset and was treated with r-tPA. Further investigation showed that the patient had 2 unruptured cerebral aneurysms. He recovered completely from the stroke and was discharged home in a few days with no deficits. Although cerebral aneurysms are considered a relative contraindication for r-tPA, our case provides evidence that it can be safely administered to these patients.