PT - JOURNAL ARTICLE AU - Zolezzi, Monica TI - Methylphenidate. An update on extended-release formulations DP - 2007 Jan 01 TA - Neurosciences Journal PG - 3--7 VI - 12 IP - 1 4099 - http://nsj.org.sa/content/12/1/3.short 4100 - http://nsj.org.sa/content/12/1/3.full SO - Neurosciences (Riyadh)2007 Jan 01; 12 AB - Methylphenidate remains the mainstay of pharmacological management in attention deficit hyperactivity disorder (ADHD). Despite having been available for over half a century, methylphenidates original formulation has been modified with the main purpose of extending its duration of action. This article will present a brief review of how these new formulations vary and how these should be selected, considering the evidence available on their effectiveness and on the individual needs of the patient.