RT Journal Article SR Electronic T1 Acute paraplegia caused by Schistosoma mansoni JF Neurosciences Journal JO Neurosciences (Riyadh) FD Prince Sultan Military Medical City SP 47 OP 51 VO 19 IS 1 A1 Hussein A. Algahtani A1 Ahmed A. Aldarmahi A1 Mohammed W. Al-Rabia A1 Saleh S. Baeesa YR 2014 UL http://nsj.org.sa/content/19/1/47.abstract AB Schistosomiasis affects over 200 million people worldwide. Involvement of the CNS is a rare occurrence. We report 2 young males who presented with rapidly progressing paraparesis associated with urinary incontinence. In both cases, MRI of the spine demonstrated a diffusely enhancing mass at the conus medullaris with extensive spinal cord edema. Laboratory investigations revealed mild peripheral eosinophilia and abnormal, but non-specific, CSF analysis. In one patient, the diagnosis was made based on a rising schistosomal titer with a positive rectal biopsy. In the other patient, spinal cord biopsy revealed a granuloma. Both cases were caused by Schistosoma mansoni and patients were treated with praziquantel and steroid therapy. They both made a remarkable neurological recovery. We emphasize that a high index of suspicion should be raised in the differential diagnosis of transverse myelitis in endemic areas.