RT Journal Article
SR Electronic
T1 Identification of posterior visual pathway lesions and MRI burden in people with Multiple Sclerosis
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 120
OP 127
DO 10.17712/nsj.2021.2.20200048
VO 26
IS 2
A1 Daqqaq, Tareef S.
YR 2021
UL http://nsj.org.sa/content/26/2/120.abstract
AB Objectives: This review systematically identifies posterior visual pathway lesions and MRI burden in people with multiple sclerosis (MS).Methods: The articles were searched through Web of Science, Medline, and Embase databases on January 2020, for English language articles from 2000 to 2019.Results: This review presents summary measures if related to MRI assessment to an overall measure of MS and visual pathway lesions. A total of 44 articles fulfilled all inclusion criteria, covering the period 2000-2019. Different atypical outcomes reveal a low risk for subsequent clinically predefined MS development, specifically in the presence of normal brain MRI. Several impairments related to quality of life have been identified as a result of the effect of retinal nerve fiber layer, ganglion cell layer, and inner plexiform layer.Conclusion: The afferent visual system in MS offers unique accessibility and structure-related functions with further understanding offered by electrophysiology, considering vision as a useful framework for examining new multiple sclerosis therapies.