RT Journal Article
SR Electronic
T1 A cross-sectional study to evaluate metabolic and demographic factors affecting cognitive function among low educated internal medicine outpatients
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 38
OP 43
DO 10.17712/nsj.2017.1.20160259
VO 22
IS 1
A1 Alakus, Feride
A1 Helvaci, Serife A.
A1 Temizel, Mustafa
A1 Arman, Yucel
YR 2017
UL http://nsj.org.sa/content/22/1/38.abstract
AB Objective: To evaluate factors affecting cognitive function in internal medicine outpatients.Methods: A total of 130 consecutive outpatients aged 50-80 years old were included in this cross-sectional study conducted at Okmeydani Training and Research Hospital, Istanbul, Turkey between March and May 2013. Cognitive function was evaluated via Standardized Mini-Mental State Examination (SMMSE) scores. Logistic regression analysis was performed to determine factors predicting poor cognitive function.Results: Mild-to-moderate cognitive impairment was noted in 39.2% of the patients. Median (interquartile range) total SMMSE scores were significantly higher in patients aged ≤60 than >60 years (27.0 (2.0) vs. 25.0 (5.0), p=0.000). Multivariate linear regression analyses revealed female gender (B, −1.27; 95% CI, −2.36 to −0.18; p=0.023) and aging (B, −0.20; 95% CI, −0.26 to −0.14; p<0.001) to result in a significant decrease in the total SMMSE scores.Conclusions: Mild-to-moderate cognitive impairment was observed in 39.2% of internal medicine outpatients. Old age and female gender were significant predictors of lower total SMMSE scores. Furthermore, besides for high language scores in hypertensive patients on combined therapy, no significant impact of hypertension or obesity was observed on the SMMSE scores.