PT  - JOURNAL ARTICLE
AU  - Nazish, Saima
AU  - Zafar, Azra
AU  - Shahid, Rizwana
AU  - Al Sulaiman, Abdullah
AU  - Alabdali, Majed
AU  - Aljaafari, Danah
AU  - Alkhamis, Fahad A.
AU  - Yasawy, Zakia M.
AU  - Ishaque, Noman
AU  - Soltan, Nehad M.
AU  - Vohra, Ejaz A.
TI  - Electrophysiologic severity of carpal tunnel syndrome in diabetic patients of the Saudi population
AID  - 10.17712/nsj.2019.1.20180217
DP  - 2019 Jan 01
TA  - Neurosciences Journal
PG  - 22--28
VI  - 24
IP  - 1
4099  - http://nsj.org.sa/content/24/1/22.short
4100  - http://nsj.org.sa/content/24/1/22.full
SO  - Neurosciences (Riyadh)2019 Jan 01; 24
AB  - Objectives: To study the frequency of multiple vascular risk factors and electrophysiological severity of carpal tunnel syndrome (CTS) in Saudi diabetic patients.Methods: This retrospective cross-sectional study was conducted in Neurology Department, King Fahd Hospital of University, Al-Khobar, Kingdom of Saudi Arabia from April 2017 to March 2018 and included 200 patients with CTS. Body parameters, such as blood pressure (BP), weight, height, and body mass index (BMI), along with laboratory and median nerve electrophysiological parameters, of diabetic and non-diabetic patients were compared, and a p-value<0.05 was considered significant.Results: Frequency of hypertension (HTN) and obesity was significantly higher in diabetic patients (p<0.05). Mean median nerve sensory amplitude (MNSA) was lower in diabetic patients (p<0.05).Non-recordable nerves, as well as bilateral and extremely severe CTS (p<0.05), were more frequently seen in diabetic patients. Age, BMI, systolic BP, low serum high density lipoprotein (HDL), high triglycerides, high fasting blood sugar, and high glycated hemoglobin (Hba1c) levels, known to affect the electrophysiological severity of CTS, had a statistically significant association with diabetes.Conclusion: Diabetes mellitus (DM) and obesity are the most commonly identified risk factors of CTS. Dyslipidemia, HTN and obesity are more frequently seen in diabetic patients with CTS. These concurrent risk factors are confounding the electrophysiological severity of CTS in these patients. Further larger-scale studies with the control of confounding factors are recommended.