RT Journal Article
SR Electronic
T1 Electrophysiologic severity of carpal tunnel syndrome in diabetic patients of the Saudi population
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 22
OP 28
DO 10.17712/nsj.2019.1.20180217
VO 24
IS 1
A1 Saima Nazish
A1 Azra Zafar
A1 Rizwana Shahid
A1 Abdullah Al Sulaiman
A1 Majed Alabdali
A1 Danah Aljaafari
A1 Fahad A. Alkhamis
A1 Zakia M. Yasawy
A1 Noman Ishaque
A1 Nehad M. Soltan
A1 Ejaz A. Vohra
YR 2019
UL http://nsj.org.sa/content/24/1/22.abstract
AB Objectives: To study the frequency of multiple vascular risk factors and electrophysiological severity of carpal tunnel syndrome (CTS) in Saudi diabetic patients.Methods: This retrospective cross-sectional study was conducted in Neurology Department, King Fahd Hospital of University, Al-Khobar, Kingdom of Saudi Arabia from April 2017 to March 2018 and included 200 patients with CTS. Body parameters, such as blood pressure (BP), weight, height, and body mass index (BMI), along with laboratory and median nerve electrophysiological parameters, of diabetic and non-diabetic patients were compared, and a p-value<0.05 was considered significant.Results: Frequency of hypertension (HTN) and obesity was significantly higher in diabetic patients (p<0.05). Mean median nerve sensory amplitude (MNSA) was lower in diabetic patients (p<0.05).Non-recordable nerves, as well as bilateral and extremely severe CTS (p<0.05), were more frequently seen in diabetic patients. Age, BMI, systolic BP, low serum high density lipoprotein (HDL), high triglycerides, high fasting blood sugar, and high glycated hemoglobin (Hba1c) levels, known to affect the electrophysiological severity of CTS, had a statistically significant association with diabetes.Conclusion: Diabetes mellitus (DM) and obesity are the most commonly identified risk factors of CTS. Dyslipidemia, HTN and obesity are more frequently seen in diabetic patients with CTS. These concurrent risk factors are confounding the electrophysiological severity of CTS in these patients. Further larger-scale studies with the control of confounding factors are recommended.