PT - JOURNAL ARTICLE AU - Kubra Isik AU - Gulin Morkavuk AU - Guray Koc AU - Zeki Odabasi TI - Sjogren’s syndrome associated with bilateral peripheral facial paralysis AID - 10.17712/nsj.2021.4.20210036 DP - 2021 Oct 01 TA - Neurosciences Journal PG - 389--391 VI - 26 IP - 4 4099 - http://nsj.org.sa/content/26/4/389.short 4100 - http://nsj.org.sa/content/26/4/389.full SO - Neurosciences (Riyadh)2021 Oct 01; 26 AB - Sjogren’s Syndrome (SS) is a chronic autoimmune disorder that may be complicated by neurological dysfunctions. The involvement of cranial nerves in SS was described as a very rare complication. Moreover, bilateral peripheral facial paralysis associated with SS has been described only in 3 patients in the literature and the first case was described by Henrik Sjogren himself in 1935. We report a 59-year-old female with bilateral peripheral facial paralysis associated with Sjogren’s syndrome. She was treated with 5-day IVIG consecutively and continued oral methylprednisolone 16mg/day and almost fully recovered at 2 months of follow-up examination. Acute bilateral peripheral facial palsy in SS is a very rare condition and Lyme disease, Guillain-Barré syndrome, HIV infection, and central nervous system lymphoma should be considered in the differential diagnosis. As a result, SS should be considered as an underlying cause of bilateral facial paralysis.