RT Journal Article SR Electronic T1 Clinical Presentation and outcome of acute disseminated encephalomyelitis in Saudi Arabia JF Neurosciences Journal JO Neurosciences (Riyadh) FD Prince Sultan Military Medical City SP 89 OP 94 DO 10.17712/nsj.2019.2.20180017 VO 24 IS 2 A1 Aldamkh, Bander Ali A1 Alamer, Abdalaziz F. A1 Altuwaijri, Mohammed M. A1 Alrumayyan, Mohammed A. A1 Alhaqbani, Abdulaziz H. A1 Alharthi, Nawaf A. A1 Aldamkh, Saeed A. A1 Aldrees, Amjad S. A1 Alrifai, Muhammad T. A1 Altuwaijri, Waleed A1 Alrumayyan, Ahmed YR 2019 UL http://nsj.org.sa/content/24/2/89.abstract AB Objectives: To evaluate the clinical presenation of acute disseminated Encephalomyelitis (ADEM) in pediatric age group, treatments, and to asses the outcome at King Abdulaziz Medical City, Riyadh, Kingdom of Saudia Arabia.Methods: The medical records of all patients younger than 18 years of age with a diagnosis of ADEM and treated at King Abdulaziz Medical City from January 1996 to Decemeber 2016 were collected. A total of 20 patients were included.Results: Of 20 patients enrolled in our study, 13 (65%) were female. Autumn and summer were the most common seasons in which ADEM presented (60%); 19 (95%) patients had a history of preceding viral illnesses. The most common neurological deficits on presentation were weakness (85%), ataxia (45%), and nystagmus (45%). Cortical and subcortical lesions (60%) were the most common finding on cranial magnetic resonance imaging. Seventeen patients (85%) received steroid only. Only 16 patients continued with follow-up, with a mean duration of 7 months. All 16 patients improved: 11 patients were recovered and 5 patients still had a neurological deficit at the clinic visits. No patient had relapsed.Conclusion: Most of the patients in this case series have an excellent outcome and attended follow-up visits and no disease relapses were identified. Further exploration of the disease is recommended.