TY - JOUR T1 - Intercorrelations of morphology with hemodynamics in intracranial aneurysms in computational fluid dynamics JF - Neurosciences Journal JO - Neurosciences (Riyadh) SP - 205 LP - 212 DO - 10.17712/nsj.2017.3.20160452 VL - 22 IS - 3 AU - Tianlun Qiu AU - Guoliang Jin AU - Wuqiao Bao AU - Haitao Lu Y1 - 2017/07/01 UR - http://nsj.org.sa/content/22/3/205.abstract N2 - Objective: To measure morphological indices and wall shear stress (WSS) of aneurysms and parent artery surface in order to explore the relationship of morphological characteristics and WSS.Methods: Data from 47 events of consecutive cerebral saccular aneurysms from 39 patients which were referred to the interventional Neuroradiology service of the Shaoxing People’s Hospital, Shaoxing, China between 2014 April and 2015 August. Wall shear stress and wall pressure (WP) of the pre-aneurysm, aneurysm and near vessel (<1.0 cm) surface were obtained. Correlation analysis was carried between morphological parameters and WSS and its ratio. WSS, WP, intra-aneurysmal flow pattern, and location of aneurysms were analyzed.Results: Impaction zone from inflow jet was located in the distal neck part of aneurysm with high WSS in 36 aneurysms (76.6%). There were significant differences in WSS between pre-aneurysm surface and near vessel (p<0.001), aneurysm (p<0.001), aneurysm and near vessel (p<0.001). Significant correlations were found between aneurysm WSS and aspect ratio (r=-0.296), aneurysm-artery WSS ratio and size ratio (r=-0.322), aspect ratio (r=-0.416).Conclusion: Uneven WSS distributes in the various part of the pre-aneurysm vessel. The impaction zone from inflow jet is located in the distal neck of aneurysm. Aspect and size ratios can effect aneurysm WSS ER -