RT Journal Article SR Electronic T1 The complex regional pain syndrome: Diagnosis and management strategies JF Neurosciences Journal JO Neurosciences (Riyadh) FD Prince Sultan Military Medical City SP 211 OP 219 DO 10.17712/nsj.2023.4.20230034 VO 28 IS 4 A1 Alshehri, Fahad S. YR 2023 UL http://nsj.org.sa/content/28/4/211.abstract AB Complex regional pain syndrome (CRPS) is a chronic disease that affects a limb following an injury or trauma. The CRPS associated with symptoms, including severe pain, swelling, as well as changes in skin color and temperature. Treatment of CRPS requires a multidisciplinary approach, with a focus on personalized treatment plans and addressing psychological factors. This review provides an overview of updates in the diagnosis and treatment of CRPS. There are clinical criteria for diagnosing CRPS, including persistent pain and swelling. The CRPS can also be diagnosed with imaging and laboratory tests. Novel insights into treatment approaches for CRPS have been gained from advances in understanding its pathophysiology. Treatment of CRPS includes both pharmacological and non-pharmacological interventions. The latest guidelines for CRPS treatment emphasize the importance of early diagnosis and intervention, personalized treatment plans, and addressing psychological factors in managing CRPS.