PT  - JOURNAL ARTICLE
AU  - Al-Khateeb, Mashael
AU  - Adem, Fatima
AU  - Moqbel, Amani
AU  - Baz, Salah
TI  - Schizophrenia following new-onset refractory status epilepticus secondary to antiphospholipid syndrome
AID  - 10.17712/nsj.2018.3.20180014
DP  - 2019 Jul 01
TA  - Neurosciences Journal
PG  - 240--244
VI  - 24
IP  - 3
4099  - http://nsj.org.sa/content/24/3/240.short
4100  - http://nsj.org.sa/content/24/3/240.full
SO  - Neurosciences (Riyadh)2019 Jul 01; 24
AB  - New-onset refractory status epilepticus (NORSE) is a drug-resistant status epilepticus that often has a catastrophic outcome. Our patient was diagnosed with NORSE and had an EEG reading that showed status epilepticus persisting for 8 months in general anesthesia. After autoimmune workup showed positive antiphospholipid antibodies, his seizure was controlled, and he was discharged with good condition apart from moderate cognitive impairment. However, he later developed schizophrenia. Although psychiatric disorders have been associated with antiphospholipid syndrome, to the best of our knowledge, it has not been reported to be associated with status epilepticus. We recommend vigilance of psychological complications of refractory status epilepticus’ patients for early psychiatric referral, diagnosis, and treatment.