TY - JOUR T1 - Schizophrenia following new-onset refractory status epilepticus secondary to antiphospholipid syndrome JF - Neurosciences Journal JO - Neurosciences (Riyadh) SP - 240 LP - 244 DO - 10.17712/nsj.2018.3.20180014 VL - 24 IS - 3 AU - Mashael Al-Khateeb AU - Fatima Adem AU - Amani Moqbel AU - Salah Baz Y1 - 2019/07/01 UR - http://nsj.org.sa/content/24/3/240.abstract N2 - New-onset refractory status epilepticus (NORSE) is a drug-resistant status epilepticus that often has a catastrophic outcome. Our patient was diagnosed with NORSE and had an EEG reading that showed status epilepticus persisting for 8 months in general anesthesia. After autoimmune workup showed positive antiphospholipid antibodies, his seizure was controlled, and he was discharged with good condition apart from moderate cognitive impairment. However, he later developed schizophrenia. Although psychiatric disorders have been associated with antiphospholipid syndrome, to the best of our knowledge, it has not been reported to be associated with status epilepticus. We recommend vigilance of psychological complications of refractory status epilepticus’ patients for early psychiatric referral, diagnosis, and treatment. ER -