RT Journal Article
SR Electronic
T1 Schizophrenia following new-onset refractory status epilepticus secondary to antiphospholipid syndrome
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 240
OP 244
DO 10.17712/nsj.2018.3.20180014
VO 24
IS 3
A1 Mashael Al-Khateeb
A1 Fatima Adem
A1 Amani Moqbel
A1 Salah Baz
YR 2019
UL http://nsj.org.sa/content/24/3/240.abstract
AB New-onset refractory status epilepticus (NORSE) is a drug-resistant status epilepticus that often has a catastrophic outcome. Our patient was diagnosed with NORSE and had an EEG reading that showed status epilepticus persisting for 8 months in general anesthesia. After autoimmune workup showed positive antiphospholipid antibodies, his seizure was controlled, and he was discharged with good condition apart from moderate cognitive impairment. However, he later developed schizophrenia. Although psychiatric disorders have been associated with antiphospholipid syndrome, to the best of our knowledge, it has not been reported to be associated with status epilepticus. We recommend vigilance of psychological complications of refractory status epilepticus’ patients for early psychiatric referral, diagnosis, and treatment.